There is good reason to limit off-target drug delivery, to minimize side effects in tissues that don’t need exposure to the drug.
Is the oral route more effective than topical?
What are the systemic effects of the oral med?
Was the study quoted in the article in any way funded by a pharmaceutical company that would be granted an exclusive license for a “new formulation,” or is it trustworthy?
There is good reason to limit off-target drug delivery, to minimize side effects in tissues that don’t need exposure to the drug.